The Duchossois Family Institute (DFI) at the University of Chicago Medicine promotes wellness through groundbreaking science on the immune system, genetics, the microbiome, and their shared environments.
Introducing a new science of wellness, the DFI aims to maximize good health and the economic, social, and personal benefits it delivers.
The DFI comprises a multidisciplinary team of scientists, physicians, data analysts, and entrepreneurship specialists who work together to accelerate development of this innovative, paradigm-shifting approach to health.
With a research, clinical, and entrepreneurial infrastructure, the Duchossois Family Institute aims to reduce the time it takes to bring scientific breakthroughs from concept to market.
Research and Discovery
Research breakthroughs by DFI scientists and University partners increase our understanding of immunology, genetics, and the microbiome.
Treatments and Interventions
Discoveries are translated into potential new treatment options, and scientists conduct clinical trials to test intervention safety and efficacy.
Partnerships with industry and investors bring new interventions to market.
Shared Resources Drive Discovery
The DFI team concentrates its efforts on driving research and discovery and translating breakthroughs into interventions that improve health. Six centralized research and discovery platforms accelerate success and allow faculty, clinicians, trainees, and students to work together efficiently:
Clinical Biorepository and Translation
Microbial Cultivation and Analysis
Next-Generation Biomarkers and Metabolomics
Microbial Sequencing and Analysis
Data Integration & Analytics: Microbiome Data Commons
Benefiting from the University of Chicago’s strengths in genomics, the immune system, the microbiome, data analytics, and entrepreneurship, the Duchossois Family Institute partners with organizations and multidisciplinary centers from across the University, including:
Senior Operations Team
The Senior Operations Team oversees research at DFI and leads the translation of discoveries into clinical breakthroughs and treatments.
Faculty Leadership Cabinet
The Faculty Leadership Cabinet works with the Senior Operations Team on new faculty recruitment, proposal evaluations, and the distribution of pilot awards and postdoctoral fellowships.
A History of Giving
The Chicago-area Duchossois family has a deep commitment to supporting science and medicine. Family members spanning three generations lead The Duchossois Family Foundation, a nonprofit organization that helps fund innovative programs in wellness and education.
To date, the Duchossois family has donated $137 million to drive innovation and transformative care at UChicago Medicine. Over nearly four decades, their generosity has supported treatment and diagnostic centers, research institutes, endowed professorships, and several cancer research funds. Some of their most transformative gifts to the University:
Richard Duchossois establishes the Beverly E. Duchossois Cancer Fund in memory of his wife. It marks the beginning of the Duchossois family’s support of UChicago Medicine.
The Duchossois family donates $21 million to fund the Duchossois Center for Advanced Medicine, the primary outpatient treatment center of UChicago Medicine.
A donation of $100 million—the largest single gift to UChicago Medicine—establishes the Duchossois Family Institute: Harnessing the Microbiome and Immunity for Human Health.